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Probuphine Implant

 One dose implanted delivers buprenorphine continuously for 6 months


we’re proud to announce that Dr. Victor Isaac at Isaac Spine Institute is the FIRST physician in the state of Tennessee to have performed Probuphine implant. This implant helps patients with Opioid Abuse Disorder.

This new technology provides a new hope for the future and we are pleased to be a part of our community’s movement towards abating opioid abuse.


PROBUPHINE contains buprenorphine, a partial opioid agonist and is indicated for the maintenance treatment of opioid dependence in patients who have achieved and sustained prolonged clinical stability on low-to-moderate doses of a transmucosal buprenorphine- containing product (i.e., doses of no more than 8 mg per day of Subutex or Suboxone sublingual tablet or generic equivalent).

PROBUPHINE should be used as part of a complete treatment program to include counseling and psychosocial support.

PROBUPHINE is not appropriate for new entrants to treatment and patients who have not achieved and sustained prolonged clinical stability, while being maintained on buprenorphine 8 mg per day or less of a Subutex or Suboxone sublingual tablet or generic equivalent. Four PROBUPHINE implants are inserted sub dermally in the upper arm for 6 months of treatment and are removed by the end of the sixth month.

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